Frailty syndrome is defined as a clinically recognizable state of increased vulnerability resulting from aging-associated declines in reserve and function across multiple physiologic systems, so that the ability to cope with everyday or acute stressors is compromised. In the United States, frailty syndrome affects 15% of the older non-nursing home population aged 65 and older and between 3.5% and 27.3% o f the older adult population worldwide (Xue et al, 2018).
Frailty is known to be a strong predictor of disability, hospitalization, institutionalization, and mortality. It can also be used to predict surgery outcomes, transplant waitlist times, cancer therapy tolerance and recovery times for older patients (Xue et al, 2018).