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Request For Letters Of Intent (LOI)
JHU OAIC Awards, Grant Year 2024-2025 LOI Due Date: Friday, April 12, 2024. Download PDF Instructions here. The National Institute on Aging-supported Johns Hopkins Claude D. Pepper Older Americans Independence Center (OAIC; https://peppercenter.jhu.edu/) is soliciting Letters of Intent (LOI) for scientific projects related to physical frailty in older adults. These proposals should aim to elucidate […]
The JHU OAIC collaboration initiative, known as the Pepper Scholars Program, consists primarily of monthly research-in-progress sessions that allow for OAIC-supported investigator interaction and discourse, along with progress updates and access to mentors and methodological experts. The program’s research-in-progress centerpiece is bolstered by an online collaboration tool, an ongoing seminar series, grant review sessions, and research facilitation […]
Frailty syndrome is defined as a clinically recognizable state of increased vulnerability resulting from aging-associated declines in reserve and function across multiple physiologic systems, so that the ability to cope with everyday or acute stressors is compromised. In the United States, frailty syndrome affects 15% of the older non-nursing home population aged 65 and older […]
Pilot and Exploratory Studies Core
The overall goal of Pilot and Exploratory Studies Core (PESC) is to cultivate and support cutting edge pilot and exploratory studies that will advance the development of effective prevention and/or therapies for frailty and hence facilitate independence in older adults. The PESC provides funding, access to biostatistical, biological, and clinical research core resources, and mentoring […]
The primary purpose of the Research Education Component (REC), formerly known as the Research Career Development Core (RCDC), is to increase the workforce of experts dedicated to scholarship on frailty and its translation into strategies to increase independence in older adults. The REC accomplishes this by identifying and selecting outstanding junior faculty investigators to pursue […]
Leadership and Administrative Core
The Leadership and Administrative Core (LAC) spearheads the collaborative mission and vision of the JHU Older Americans Independence Center (OAIC). The LAC serves as the driving force in identifying the next generation of research on frailty, supports research planning and recruitment of investigators, and sets and monitors progress benchmarks. The core administrates the OAIC and […]
Resource Core 1: Biostatistics Core
The Biostatistics Core (OAIC Resource Core 1, or RC1), seeks to empower our institutions’ scientists with the quantitative support and expertise needed to create and translate into clinical practice the next generations of research on frailty. The functions supplied by the Biostatistics Core of the Johns Hopkins Older Americans Independence Center have been central in […]
Resource Core 2: Biological Mechanisms Core
The rationale for the Biological Mechanisms Core (Resource Core 2, or RC2) is to provide the expertise, technology access and infrastructure, mentoring, and training necessary to facilitate the highest quality etiologic research in frailty. RC2-supported projects have made substantial scientific progress towards the elucidation of biological pathways critical to frailty and to highlighting biological pathways […]
Resource Core 3: Clinical Translation Core
In order to effectively meet JHU OAIC’s goal of translating frailty-related etiological discoveries into clinical studies that help maintain independence in older adults, and to overcome the substantial barriers to success in clinical investigation for junior investigators, the OAIC RC3 provides to supported OAIC investigators: Dr. Todd Brown, an endocrinologist with considerable human subjects research […]
Jackie Langdon serves as a senior research program manager for both the Healthy Aging Studies Unit (HASU) clinical research program and the laboratory operations of Biology of Healthy Aging (BOHA) work group in the Division of Geriatric Medicine and Gerontology at Johns Hopkins University. Her research expertise is the organization and integration of clinical and […]
